USP Reference Standards -S, chemical structure, molecular formula, Reference Standards

USP Saccharin RS— Do not dry.Keep container tightly closed.

Add the following:

USP Saccharin Calcium RS —Dry at 105

for 2hours before using.

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Add the following:

USP Saccharin Sodium RS —Dry at 105

for 2hours before using.

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USP Salicylamide RS— Dry portion over silica gel for 18hours before using.Keep container tightly closed.

USP Salicylic Acid RS— Dry portion over silica gel for 3hours before using.Keep container tightly closed.

USP Salicylic Acid Tablets RS(Dissolution Calibrator,Non-disintegrating)— The label states the nominal weight of each tablet.Use only whole tablets—extra tablets are provided.Remove any surface dust with a soft brush before using.Keep container tightly closed.Store in a desiccator or in a dry place at room temperature.

USP Salsalate RS— Dry portion in vacuum at 60

for 3hours before using.Keep container tightly closed.

USP Saquinavir Mesylate RS.

USP Saquinavir Related Compound A RS [N-tert-butyl-decahydro-2-[2(R)-hydroxy-4-phenyl-3(S)-[[N-(2-quinolylcarbonyl)-D-asparaginyl]amino]butyl]-(4aS,8aS)-isoquinoline-3(S)-carboxamide] (C38H50N6O5

670.84) .

USP Scopolamine Hydrobromide RS— Dry portion at 105

for 3hours before using.Keep container tightly closed and protected from light.

USP Scopoletin RS— Do not dry.Keep container tightly closed.Store in a refrigerator.Protect from light.

USP Secobarbital RS— Dry portion over silica gel for 18hours before using.Keep container tightly closed.

USP Selegiline Hydrochloride RS— Dry portion in vacuum at 60

for 3hours before using.Keep container tightly closed and protected from light.

USP Selenomethionine RS.

USP Sennosides RS— Do not dry before using.Dry a separate portion in vacuum at 100

to constant weight to obtain loss on drying for quantitative analyses.Keep container tightly closed.Material is extremely hygroscopic.

USPL-Serine RS— Dry portion at 105

for 3hours before using.Keep container tightly closed.

USP Sevoflurane RS— Do not dry.Keep container tightly closed.Store in a refrigerator.

USP Sevoflurane Related Compound A RS [1,1,1,3,3-pentafluoroisopropenyl fluoromethyl ether] (C4H2F6O

179.97) —Do not dry.After opening ampul,store in a tightly closed container.Store in a refrigerator.

USP Silver Sulfadiazine RS— Dry portion at 105

for 1hour before using.Keep container tightly closed.Protect from light.

USP Silybin RS— Do not dry before using.For quantitative applications use a value of 0.94mg silybin per mg on the as-is basis.Keep container tightly closed and protected from light.Store in a freezer.

USP Silydianin RS— Do not dry before using.Keep container tightly closed.Protect from light.Store in freezer.

USP Simethicone RS— Mix well before using.Keep container tightly closed.

USP Simvastatin RS— Do not dry before using.Keep container tightly closed,protected from light,and store in a freezer.

USP Sincalide RS.

USP Sisomicin Sulfate RS— Do not dry.[Caution:Hygroscopic. ]Correct for volatiles content as determined by heating a separate 100-mg portion at 110

at a pressure of 5mm of mercury or less for 3hours.Keep container tightly closed,protected from light,and store in a cold place.

USPb-Sitosterol RS— Do not dry.Store at room temperature.

USP Sodium Ascorbate RS— Do not dry.Keep container tightly closed.Protect from light.

USP Sodium Butyrate RS— Do not dry before using.Keep container tightly closed.This material is hygroscopic.

USP Sodium Fluoride RS— Dry portion at 150

for 4hours before using.Keep the container tightly closed.

USP Sodium Lactate RS— Dry portion in vacuum at 60

for 4hours before using.Keep container tightly closed.

USP Sodium Nitroprusside RS— This is the dihydrate form.Do not dry before using.Keep container tightly closed.Protect from light.

USP Sodium Propionate RS— Do not dry before using.Keep container tightly closed.

USP Sodium Stearyl Fumarate RS— Do not dry before using.Keep container tightly closed.

USP Somatropin RS— Store in a tight container in a freezer.When reconstituted,store in a cold place,and use within 24hours.

USP1,4-Sorbitan RS (C6H12O5

164.16) —Do not dry before using.Keep container tightly closed.

USP Sorbitol RS— Do not dry before using.Keep container tightly closed.

USP Sotalol Hydrochloride RS— Do not dry.Keep container tightly closed.Protect from light.Store in a refrigerator.

USP Sotalol Hydrochloride Related Compound A RS [N[(4-[[(1-methylethyl)amino]acetyl]phenyl]methanesulfonamide monohydrochloride] (C12H18N2O3S·HCl

306.81) —Do not dry.Keep container tightly closed.Store in a refrigerator.

USP Sotalol Hydrochloride Related Compound B RS [N-(4-formylphenyl)methanesulfonamide] (C8H9NO3S

199.23) —Do not dry.Keep container tightly closed.Store in a refrigerator.

USP Sotalol Hydrochloride Related Compound C RS [N-[4-[2-[(1-methylethyl)amino]ethyl]phenyl]methanesulfonamide monohydrochloride] (C12H20N2O2S·HCl

292.83) —Do not dry.Keep container tightly closed.Store in a refrigerator.

Change to read:

USP Spectinomycin Hydrochloride RS—

This is the pentahydrate form of spectinomycin hydrochloride.

USP28Do not dry before using.Keep container tightly closed.Protect from light.Store in a

refrigerator.

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USP Spironolactone RS— Dry portion at 105

for 2hours before using.Keep container tightly closed.

USP Squalane RS— Do not dry before using.After opening ampul transfer the contents to a tightly closed container.

USP Stanozolol RS— Dry portion at a pressure not exceeding 5mm of mercury at 100

to constant weight before using.Keep container tightly closed.Protect from light.

USP Stearic Acid RS— Dry portion over silica gel for 4hours before using.Keep container tightly closed.

USP Stearyl Alcohol RS— Do not dry before using.Keep container tightly closed.

USP Powdered St.John’s Wort Extract RS.

USP Streptomycin Sulfate RS— Dry portion in vacuum at a pressure not exceeding 5mm of mercury at 60

for 3hours before using.Keep container tightly closed.Protect from light.Store in a cold place.

USP Succinylcholine Chloride RS— Do not dry;determine the water content potentiometrically at time of use for quantitative analyses.Keep container tightly closed.Store in a desiccator.

USP Succinylmonocholine Chloride RS— Dry portion in vacuum at 55

for 16hours.Keep container tightly closed.

USP Sucralose RS —Do not dry.Keep container tightly closed.

USP Sucrose RS— Do not dry before use.Keep container tightly closed.

USP Sufentanil Citrate RS— Dry portion in vacuum at 60

for 2hours before using.Keep container tightly closed.

USP Sulbactam RS— Do not dry before using.Keep container tightly closed,and store in a freezer.

USP Sulconazole Nitrate RS— Dry portion in vacuum at 80

for 3hours before using.Keep container tightly closed.

USP Sulfabenzamide RS— Dry portion at 105

for 2hours before using.Keep container tightly closed.Protect from light.

USP Sulfacetamide RS— Dry portion at 105

for 2hours before using.Keep container tightly closed.Protect from light.

USP Sulfacetamide Sodium RS— Determine the water content titrimetrically at time of use.This material is very hygroscopic.Store over silica gel.Keep container tightly closed.Protect from light.Store in a cool place.

USP Sulfachlorpyridazine RS— Dry portion at 105

for 3hours before using.Keep container tightly closed and protected from light.

USP Sulfadiazine RS— Dry portion at 105

for 2hours before using.Keep container tightly closed.Protect from light.

USP Sulfadimethoxine RS— Do not dry.Keep container tightly closed.Protect from light.

Change to read:

USP Sulfadoxine RS—

Do not dry.

USP28Keep container tightly closed.Protect from light.

USP Sulfamerazine RS— Dry portion at 105

for 2hours before using.Keep container tightly closed.Protect from light.

USP Sulfamethazine RS— Dry portion at 105

for 2hours before using.Keep container tightly closed.Protect from light.

USP Sulfamethizole RS— Dry portion at 105

for 2hours before using.Keep container tightly closed.Protect from light.

USP Sulfamethoxazole RS— Dry portion at 105

for 4hours before using.Keep container tightly closed.Protect from light.

USP Sulfamethoxazole N4-Glucoside RS— Do not dry;use as is.Keep container tightly closed.Protect from light.

USP Sulfanilamide RS— Dry portion at 105

for 3hours before using.Keep container tightly closed and protected from light.

USP Sulfanilamide Melting Point RS— Dry portion over silica gel for 16hours before using.The melting range is the temperature range within which the substance coalesces and is completely melted when tested by the USPcapillary tube method.Keep container tightly closed and protected from light.

USP Sulfanilic Acid RS (C6H7NO3S

173.19) —Dry portion at 105

for 4hours before using.Keep container tightly closed.Protect from light.

USP Sulfapyridine RS— Do not dry.Keep container tightly closed.Protect from light.

USP Sulfapyridine Melting Point RS— Dry portion over silica gel for 16hours before using.When melted by the USPcapillary tube method,Class Ia in the general chapter Melting Range or Temperature á741ñ,the observed range falls within the indicated acceptance range.Keep container tightly closed.

USP Sulfaquinoxaline RS.

USP Sulfaquinoxaline Related Compound A RS [N1-N2-diquinoxalin-2-ylsulfanilamide] (C22H16N6SO2

428.50) .

USP Sulfasalazine RS— Dry portion at 105

for 2hours before using.Keep container tightly closed.Protect from light.

USP Sulfathiazole RS— Dry portion at 105

for 2hours before using.Keep container tightly closed.Protect from light.

USP Sulfinpyrazone RS— Do not dry.Keep container tightly closed.

USP Sulfisoxazole RS— Dry portion at 105

for 2hours before using.Keep container tightly closed.Protect from light.

USP Sulfisoxazole Acetyl RS— Dry portion at 105

for 3hours before using.Keep container tightly closed.Protect from light.

USP Sulindac RS— Dry portion in vacuum at 100

for 2hours before using.Keep container tightly closed.

USP Sulisobenzone RS.

Add the following:

USP Sumatriptan RS— Do not dry.Keep container tightly closed.Protect from light.Store in a refrigerator.

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Add the following:

USP Sumatriptan Succinate RS [1H-indole-5-methanesulfonamide,3-[2-(dimethylamino)ethyl]-N-methyl-,butanedioate (1:1)] (C14H21N3O2S·C4H6O4

413.49) —Do not dry.Keep container tightly closed.Protect from light.Store in a refrigerator.

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Add the following:

USP Sumatriptan Succinate Related Compound A RS [[3-[2-(dimethylamino)ethyl]-2-[[3-[2-(dimethylamino)ethyl]-1H-indol-5-yl]methyl]-1H-indol-5-yl]-N-methylmethanesulfonamide succinate salt] (C27H37N5O2S·C4H6O4

613.77) —Do not dry.Keep container tightly closed.Protect from light.Store in a refrigerator.

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Add the following:

USP Sumatriptan Succinate Related Compound C RS [[3-[2-(dimethylamino)ethyl]-1-(hydroxymethyl)-1H-indol-5-yl]-N-methylmethanesulfonamide succinate salt] (C15H23N3O3S·0.5C4H6O4

384.47) .

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Add the following:

USP Sumatriptan Succinate Related Impurities RS [Mixture of sumatriptan succinate,[3-[2-(methylamino)ethyl]-1H-indol-5-yl]-N-methylmethanesulfonamide maleate salt,sumatriptan succinate related compound C,[3-[2-(dimethylamino-N-oxide)ethyl]-1H-indol-5-yl]-N-methylmethanesulfonamide,and [3-[2-(aminoethyl)-1H-indol-5-yl]-N-methylmethanesulfonamide] .

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USP Suprofen RS— Dry portion in vacuum at 70

for 4hours before using.Keep container tightly closed.