USP Saccharin RS—
Do not dry. Keep container tightly closed.
USP Saccharin Calcium RS
—Dry portion at 105

for 2 hours before using.
USP Saccharin Sodium RS
—Dry portion at 105

for 2 hours before using.
USP Salicylamide RS—
Dry portion over silica gel for 18 hours before using. Keep container tightly closed.
USP Salicylic Acid RS—
Do not dry. Keep container tightly closed.
USP Salicylic Acid Tablets RS (Dissolution Calibrator, Non-disintegrating)—
The label states the nominal weight of each tablet. Use only whole tablets—extra tablets are provided. Remove any surface dust with a soft brush before using. Keep container tightly closed. Store in a desiccator or in a dry place at room temperature.
USP Salsalate RS—
Dry portion in vacuum at 60

for 3 hours before using. Keep container tightly closed.
USP Saquinavir Mesylate RS.
USP Saquinavir Related Compound A RS
[N-tert-butyl-decahydro-2-[2(
R)-hydroxy-4-phenyl-3(
S)-[[
N-(2-quinolylcarbonyl)-
D-asparaginyl]amino]butyl]-(4a
S,8a
S)-isoquinoline-3(
S)-carboxamide
]
(C
38H
50N
6O
5

670.84)
.
USP Scopolamine Hydrobromide RS—
Dry portion at 105

for 3 hours before using. Keep container tightly closed and protected from light.
USP Scopoletin RS—
Do not dry. Keep container tightly closed. Store in a refrigerator. Protect from light.
USP Secobarbital RS—
Dry portion over silica gel for 18 hours before using. Keep container tightly closed.
USP Selegiline Hydrochloride RS—
Dry portion in vacuum at 60

for 3 hours before using. Keep container tightly closed and protected from light.
USP Selenomethionine RS.
USP Sennosides RS—
Do not dry before using. Dry a separate portion in vacuum at 100

to constant weight to obtain loss on drying for quantitative analyses. Keep container tightly closed. Material is extremely hygroscopic.
USP L-Serine RS—
Dry portion at 105

for 3 hours before using. Keep container tightly closed.
USP Sevoflurane RS—
Do not dry. Keep container tightly closed. Store in a refrigerator.
USP Sevoflurane Related Compound A RS
[1,1,1,3,3-pentafluoroisopropenyl fluoromethyl ether
]
(C
4H
2F
6O

179.97)
—Do not dry. After opening ampul, store in a tightly closed container. Store in a refrigerator.
USP Sevoflurane Related Compound B RS
[1,1,1,3,3,3-hexafluoro-2-methoxy-propane]
—Do not dry. After opening the ampul, store the material in a tightly closed container. Store in a refrigerator.
USP Sevoflurane Related Compound C RS
[1,1,1,3,3,3-hexafluoro-2-propanol]
—Do not dry. After opening the ampul, store the material in a tightly closed container. Store in a refrigerator.
USP Sevomethyl Ether RS
[1,1,1,3,3,3-hexafluoro-2-methoxy-propane]
—Do not dry.
USP Silver Sulfadiazine RS—
Dry portion at 105

for 1 hour before using. Keep container tightly closed. Protect from light.
USP Silybin RS—
Do not dry before using. Keep container tightly closed and protected from light. Store in a freezer.
USP Silydianin RS—
Do not dry before using. Keep container tightly closed. Protect from light. Store in freezer.
USP Simethicone RS—
Mix well before using. Keep container tightly closed. After opening, store under inert gas.
USP Simvastatin RS—
Do not dry before using. Keep container tightly closed, protected from light, and store in a freezer.
USP Sincalide RS.
USP Sisomicin Sulfate RS—
Do not dry.
[Caution:Hygroscopic.
] Correct for volatiles content as determined by heating a separate 100-mg portion at 110

at a pressure of 5 mm of mercury or less for 3 hours. Keep container tightly closed, protected from light, and store in a cold place.
USP
-Sitosterol RS—
Do not dry. For quantitative applications, determine the water content titrimetrically at the time of use. Keep container tightly closed. This material is hygroscopic.
USP Human Fibroblast-Derived Temporary Skin Substitute Reference Photomicrographs VRS.
USP Sodium Ascorbate RS—
Do not dry. Keep container tightly closed. Protect from light.
USP Sodium Butyrate RS—
Do not dry before using. Keep container tightly closed. This material is hygroscopic.
Change to read:
USP Sodium Fluoride RS—

Do not dry.
USP29 Keep container tightly closed.
USP Sodium Lactate RS—
Dry portion in vacuum at 60

for 4 hours before using. Keep container tightly closed.
USP Sodium Nitroprusside RS—
This is the dihydrate form. Do not dry before using. Keep container tightly closed. Protect from light.
USP Sodium Propionate RS—
Do not dry before using. Keep container tightly closed.
USP Sodium Stearyl Fumarate RS—
Do not dry before using. Keep container tightly closed.
USP Somatropin RS—
Store in a tight container in a freezer. When reconstituted, store in a cold place, and use within 24 hours.
USP 1,4-Sorbitan RS
(C
6H
12O
5

164.16)
—Do not dry before using. Keep container tightly closed.
USP Sorbitol RS—
Do not dry before using. Keep container tightly closed.
USP Sotalol Hydrochloride RS—
Do not dry. Keep container tightly closed. Protect from light. Store in a refrigerator.
USP Sotalol Hydrochloride Related Compound A RS
[N[(4-[[(1-methylethyl)amino]acetyl]phenyl]methanesulfonamide monohydrochloride
]
(C
12H
18N
2O
3S·HCl

306.81)
—Do not dry. Keep container tightly closed. Store in a refrigerator.
USP Sotalol Hydrochloride Related Compound B RS
[N-(4-formylphenyl)methanesulfonamide
]
(C
8H
9NO
3S

199.23)
—Do not dry. Keep container tightly closed. Store in a refrigerator.
USP Sotalol Hydrochloride Related Compound C RS
[N-[4-[2-[(1-methylethyl)amino]ethyl]phenyl]methanesulfonamide monohydrochloride
]
(C
12H
20N
2O
2S·HCl

292.83)
—Do not dry. Keep container tightly closed. Store in a refrigerator.
USP Spectinomycin Hydrochloride RS—
This is the pentahydrate form of Spectinomycin Hydrochloride. Do not dry before using. Keep container tightly closed. Protect from light. Store in a refrigerator.
USP Spironolactone RS—
Dry portion at 105

for 2 hours before using. Keep container tightly closed.
USP Squalane RS—
Do not dry before using. After opening ampul, transfer the contents to a tightly closed container.
USP Stanozolol RS—
Dry portion at a pressure not exceeding 5 mm of mercury at 100

to constant weight before using. Keep container tightly closed. Protect from light.
Change to read:
USP Stavudine RS—

Do not dry. Keep container tightly closed. Protect from light. Store in a freezer.
USP29
Change to read:
USP Stavudine System Suitability Mixture RS—
It is a mixture of stavudine and the following related compounds: thymidine, thymine, alpha-stavudine, and
xylo-thymidine.

Do not dry. Keep container tightly closed. Protect from light. Store in a refrigerator.
USP29
USP Stearic Acid RS—
Do not dry. Keep container tightly closed.
USP Stearyl Alcohol RS—
Do not dry before using. Keep container tightly closed.
USP Stearoyl Polyoxylglycerides RS—
Do not dry. Keep container tightly closed.
USP Powdered St. John’s Wort Extract RS.
USP Streptomycin Sulfate RS—
Dry portion in vacuum at a pressure not exceeding 5 mm of mercury at 60

for 3 hours before using. Keep container tightly closed. Protect from light. Store in a cold place.
USP Succinylcholine Chloride RS—
Do not dry; determine the water content potentiometrically at time of use for quantitative analyses. Keep container tightly closed. Store in a desiccator.
USP Succinylmonocholine Chloride RS—
Dry portion in vacuum at 55

for 16 hours. Keep container tightly closed.
USP Sucralose RS
—Do not dry. Keep container tightly closed.
USP Sucrose RS—
Do not dry before use. Keep container tightly closed.
USP Sufentanil Citrate RS—
Dry portion in vacuum at 60

for 2 hours before using. Keep container tightly closed.
USP Sulbactam RS—
Do not dry before using. Keep container tightly closed, and store in a freezer.
USP Sulconazole Nitrate RS—
Dry portion in vacuum at 80

for 3 hours before using. Keep container tightly closed.
USP Sulfabenzamide RS—
Dry portion at 105

for 2 hours before using. Keep container tightly closed. Protect from light.
USP Sulfacetamide RS—
Dry portion at 105

for 2 hours before using. Keep container tightly closed. Protect from light.
USP Sulfacetamide Sodium RS—
Determine the water content titrimetrically at time of use. This material is very hygroscopic. Store over silica gel. Keep container tightly closed. Protect from light. Store in a cool place.
USP Sulfachlorpyridazine RS—
Dry portion at 105

for 3 hours before using. Keep container tightly closed and protected from light.
USP Sulfadiazine RS—
Dry portion at 105

for 2 hours before using. Keep container tightly closed. Protect from light.
USP Sulfadimethoxine RS—
Do not dry. Keep container tightly closed. Protect from light.
USP Sulfadoxine RS—
Do not dry. Keep container tightly closed. Protect from light.
USP Sulfamerazine RS—
Dry portion at 105

for 2 hours before using. Keep container tightly closed. Protect from light.
USP Sulfamethazine RS—
Dry portion at 105

for 2 hours before using. Keep container tightly closed. Protect from light.
USP Sulfamethizole RS—
Dry portion at 105

for 2 hours before using. Keep container tightly closed. Protect from light.
USP Sulfamethoxazole RS—
Dry portion at 105

for 4 hours before using. Keep container tightly closed. Protect from light.
USP Sulfamethoxazole N4-Glucoside RS—
Do not dry; use as is. Keep container tightly closed. Protect from light.
USP Sulfanilamide RS—
Dry portion at 105

for 3 hours before using. Keep container tightly closed and protected from light.
USP Sulfanilamide Melting Point RS—
Dry portion over silica gel for 16 hours before using. The melting range is the temperature range within which the substance coalesces and is completely melted when tested by the USP capillary tube method. Keep container tightly closed and protected from light.
USP Sulfanilic Acid RS
(C
6H
7NO
3S

173.19)
—Dry portion at 105

for 4 hours before using. Keep container tightly closed. Protect from light.
USP Sulfapyridine RS—
Do not dry. Keep container tightly closed. Protect from light.
USP Sulfapyridine Melting Point RS—
Dry portion over silica gel for 16 hours before using. When melted by the USP capillary tube method,
Class Ia in the general chapter
Melting Range or Temperature
741
, the observed range falls within the indicated acceptance range. Keep container tightly closed.
USP Sulfaquinoxaline RS.
Change to read:
USP Sulfaquinoxaline Related Compound A RS
[N1-
N2-diquinoxalin-2-ylsulfanilamide
]
(C
22H
16N
6SO
2

428.50)
—

Do not dry. Keep container tightly closed. Protect from light.
USP29
USP Sulfasalazine RS—
Dry portion at 105

for 2 hours before using. Keep container tightly closed. Protect from light.
USP Sulfathiazole RS—
Dry portion at 105

for 2 hours before using. Keep container tightly closed. Protect from light.
USP Sulfinpyrazone RS—
Do not dry. Keep container tightly closed.
USP Sulfisoxazole RS—
Dry portion at 105

for 2 hours before using. Keep container tightly closed. Protect from light.
USP Sulfisoxazole Acetyl RS—
Dry portion at 105

for 3 hours before using. Keep container tightly closed. Protect from light.
USP Sulindac RS—
Dry portion in vacuum at 100

for 2 hours before using. Keep container tightly closed.
USP Sulisobenzone RS.
USP Sumatriptan RS—
Do not dry. Keep container tightly closed. Protect from light. Store in a refrigerator.
USP Sumatriptan Succinate RS
[1
H-indole-5-methanesulfonamide, 3-[2-(dimethylamino)ethyl]-
N-methyl-, butanedioate (1:1)
]
(C
14H
21N
3O
2S·C
4H
6O
4

413.49)
—Do not dry. Keep container tightly closed. Protect from light. Store in a refrigerator.
USP Sumatriptan Succinate Related Compound A RS
[[3-[2-(dimethylamino)ethyl]-2-[[3-[2-(dimethylamino)ethyl]-1
H-indol-5-yl]methyl]-1
H-indol-5-yl]-
N-methylmethanesulfonamide succinate salt
]
(C
27H
37N
5O
2S·C
4H
6O
4

613.77)
—Do not dry. Keep container tightly closed. Protect from light. Store in a refrigerator.
USP Sumatriptan Succinate Related Compound C RS
[[3-[2-(dimethylamino)ethyl]-1-(hydroxymethyl)-1
H-indol-5-yl]-
N-methylmethanesulfonamide succinate salt
]
(C
15H
23N
3O
3S· 0.5 C
4H
6O
4

384.47)
.
Change to read:
USP Sumatriptan Succinate Related Impurities RS
[Mixture of sumatriptan succinate, [3-[2-(methylamino)ethyl]-1
H-indol-5-yl]-
N-methylmethanesulfonamide maleate salt, sumatriptan succinate related compound C, [3-[2-(dimethylamino-
N-oxide)ethyl]-1
H-indol-5-yl]-
N-methylmethanesulfonamide, and [3-[2-(aminoethyl)-1
H-indol-5-yl]-
N-methylmethanesulfonamide
]
—

Do not dry. Keep container tightly closed. Protect from light. Store in a refrigerator.
USP29
USP Suprofen RS—
Dry portion in vacuum at 70

for 4 hours before using. Keep container tightly closed.