General Chapters: USP Reference Standards

USP Dacarbazine RS— Keep container tightly closed and protected from light, and store in a refrigerator. Dry portion in vacuum over phosphorus pentoxide at 60

for 2 hours before using.

USP Dacarbazine Related Compound A RS [5-aminoimidazole-4-carboxamide hydrochloride] —Do not dry before using. Keep container tightly closed and protected from light, and store in a refrigerator.

USP Dacarbazine Related Compound B RS [2-azahypoxanthine] (C4H3N5O

137.10) —This is the monohydrate form of 2-azahypoxanthine. Do not dry before using. Keep container tightly closed and protected from light, and store in a refrigerator.

USP Dactinomycin RS— Dry portion in vacuum at a pressure not exceeding 5 mm of mercury at 60

for 3 hours before using. Keep container tightly closed. Protect from light. Store in a cold place.

USP Danazol RS— Dry portion at a pressure not exceeding 5 mm of mercury at 60

to constant weight before using. Keep container tightly closed. Protect from light.

USP Danthron RS— Dry portion over silica gel for 4 hours before using. Keep container tightly closed.

USP Dapsone RS— Dry portion at 105

for 3 hours before using. Keep container tightly closed. Protect from light.

USP Daunorubicin Hydrochloride RS— Do not dry before using. For quantitative applications, determine the water content titrimetrically at the time of use. Keep container tightly closed. Protect from light. Store in a freezer. Allow to equilibrate to room temperature before opening.

USP Decoquinate RS.

USP Deferoxamine Mesylate RS— Do not dry; determine the water content titrimetrically at the time of use. Keep container tightly closed.

USP Dehydrocarteolol Hydrochloride RS [5-(3-tert-butylamino-2-hydroxy)-propoxycarbostyril hydrochloride] (C16H22N2O3·HCl

326.82) —Do not dry. Use as is. Keep container tightly closed and protected from light.

USP Dehydrocholic Acid RS— Dry portion at 105

for 2 hours before using. Keep container tightly closed.

USP Demecarium Bromide RS— Keep container tightly closed. Protect from light. Store in a cool place.

USP Demeclocycline Hydrochloride RS— Dry portion in vacuum at a pressure not exceeding 5 mm of mercury at 60

for 3 hours before using. Keep container tightly closed. Protect from light. Store in a cold place.

USP Denatonium Benzoate RS— This material is the anhydrous form of denatonium benzoate. Dry portion at 105

for 2 hours before using. Keep container tightly closed.

USP Cryopreserved Human Fibroblast-Derived Dermal Substitute Reference Photomicrographs VRS.

USP Desacetyl Diltiazem Hydrochloride RS (C20H24N2O3S·HCl

408.95) —Do not dry. Keep container tightly closed. Protect from light.

USP Desflurane RS— Do not dry. After opening ampul, store in a tightly closed container. Store in a refrigerator.

USP Desflurane Related Compound A RS [bis-(1,2,2,2-tetrafluoroethyl)ether] (C4H2F8O

218.05) —Do not dry. After opening the ampul, store in a tightly closed container. Store in a refrigerator.

USP Desipramine Hydrochloride RS— Dry portion in vacuum at 105

for 2 hours before using. Keep container tightly closed.

USP Deslanoside RS— Dry portion in vacuum over phosphorus pentoxide to constant weight before using. Keep container tightly closed. Protect from light. This material is hygroscopic.

USP Desogestrel Related Compound C RS [3-keto-desogestrel] (C22H28O2

324.46) —Do not dry.

Add the following:

USP Desoaminylazithromycin RS —Do not dry. Keep container tightly closed. Store in a refrigerator.

USP29

USP Desoximetasone RS— Dry portion at 105

to constant weight before using. Keep container tightly closed.

USP Desoxycorticosterone Acetate RS— Do not dry. Keep container tightly closed.

USP Desoxycorticosterone Pivalate RS— Dry portion at 105

for 2 hours before using. Keep container tightly closed and protected from light.

USP Dexamethasone RS— Keep container tightly closed. Dry portion at 105

for 3 hours before using.

USP Dexamethasone Acetate RS— Dry portion in vacuum at 105

for 3 hours before using. Keep container tightly closed.

USP Dexamethasone Phosphate RS— This material is Dexamethasone Phosphate Acid. Dry portion at a pressure of 5 mm of mercury at 40

to constant weight before using. Keep container tightly closed.

USP Dexbrompheniramine Maleate RS— Dry portion at 65

for 4 hours before using. Keep container tightly closed. Protect from light.

USP Dexchlorpheniramine Maleate RS— Do not dry. Keep container tightly closed. Protect from light. Store in a refrigerator.

USP Dexpanthenol RS— Do not dry; determine the water content titrimetrically before using for quantitative analyses. Keep container tightly closed and protected from moisture.

USP Dextran 1 RS— Dry portion at 105

for 5 hours before using. Keep container tightly closed. Store in a desiccator.

USP Dextran 4 Calibration RS— Do not dry. Store at room temperature. Keep container tightly closed.

USP Dextran 10 Calibration RS— Do not dry. Store at room temperature. Keep container tightly closed.

USP Dextran 40 RS.

USP Dextran 40 Calibration RS— Do not dry. Store at room temperature. Keep container tightly closed.

USP Dextran 40 System Suitability RS.

USP Dextran 70 RS.

USP Dextran 70 Calibration RS— Do not dry. Store at room temperature. Keep container tightly closed.

USP Dextran 70 System Suitability RS.

USP Dextran 250 Calibration RS— Do not dry. Store at room temperature. Keep container tightly closed.

USP Dextran T-10 RS— Dry at 105

for 3 hours before using. Keep container tightly closed.

USP Dextran Vo Marker RS.

USP Dextroamphetamine Sulfate RS— Dry portion at 105

for 2 hours before using. Keep container tightly closed.

USP Dextromethorphan RS— Do not dry; determine the water content titrimetrically at the time of use. Keep container tightly closed.

USP Dextromethorphan Hydrobromide RS— Do not dry; determine the water content titrimetrically at time of use. Keep container tightly closed.

USP Dextrose RS— This is the anhydrous form of dextrose. Dry portion at 105

for 16 hours before using. Keep container tightly closed.

USP Diacetylated Monoglycerides RS— Keep container tightly closed. Protect from light.

USP Diacetylfluorescein RS (C24H16O7

416.39) —Keep container tightly closed. Dry portion at 105

for 4 hours before using. Keep container tightly closed. Protect from light.

USP Diatrizoic Acid RS— This material is the hydrous form of diatrizoic acid. Dry portion at 105

for 4 hours before using. Keep container tightly closed.

USP Diatrizoic Acid Related Compound A RS [5-acetamido-3-amino-2,4,6-triiodobenzoic acid] (C9H7I3N2O3

571.88) —Dry portion at 105

for 4 hours before using. Keep container tightly closed and protected from light.

USP Diazepam RS— Do not dry. Keep container tightly closed. Protect from light.

USP Diazepam Related Compound A RS [2-methylamino-5-chlorobenzophenone] (C14H12ClNO

245.71) —Do not dry before using. Keep container tightly closed. Protect from light.

USP Diazepam Related Compound B RS [3-amino-6-chloro-1-methyl-4-phenylcarbostyril] (C16H13ClN2O

284.74) —Do not dry. Keep container tightly closed. Protect from light.

USP Diazoxide RS— Dry portion at 105

for 4 hours before using. Keep container tightly closed.

USP Dibucaine Hydrochloride RS— Dry portion at 80

for 5 hours before using. Keep container tightly closed. Protect from light.

USP Dibutyl Phthalate RS— Do not dry. After opening ampul, store the materials in a tightly closed container.

USP Dichloralphenazone RS.

USP Dichlorphenamide RS— Do not dry. Keep container tightly closed.

USP Diclofenac Sodium RS— Dry portion at 105

for 3 hours before using. Keep container tightly closed and protected from light.

USP Diclofenac Related Compound A RS [N-(2,6-dichlorophenyl)indolin-2-one] (C14H9Cl2NO

278.14) —Do not dry. Keep container tightly closed and protected from light.

USP Dicloxacillin Sodium RS— Do not dry before using. Determine the water content titrimetrically at the time of use. Keep container tightly closed. Protect from light. Store in a cold place.

USP Dicyclomine Hydrochloride RS— Dry portion at 105

for 4 hours before using. Keep container tightly closed.

USP Dienestrol RS— Dry portion at 105

for 2 hours before using. Keep container tightly closed.

USP Diethylcarbamazine Citrate RS— Do not dry before using. Keep container tightly closed.

USP Diethylene Glycol Monoethyl Ether RS.

USP Diethyl Phthalate RS— Do not dry before using. Keep container tightly closed.

USP Diethylpropion Hydrochloride RS— Dry portion over silica gel for 4 hours before using. Keep container tightly closed. Protect from light. Use within 2 years of purchase.

USP Diethylstilbestrol RS— Dry portion at 105

for 2 hours before using. Keep container tightly closed. Protect from light.

USP Diethylstilbestrol Diphosphate RS.

USP Diethyltoluamide RS— Do not dry; determine the water content titrimetrically at the time of use. Keep container tightly closed.

USP Diflorasone Diacetate RS— Dry portion in vacuum at 60

and at a pressure not exceeding 5 mm of mercury for 16 hours before using. Keep container tightly closed.

USP Diflunisal RS— Dry portion in vacuum at 60

and at a pressure not exceeding 5 mm of mercury for 4 hours before using. Keep container tightly closed.

USP Digitalis RS— Do not dry before using. Keep container tightly closed, and store in a cool place.

USP Digitoxin RS— Dry portion in vacuum at 105

for 1 hour before using. Keep container tightly closed.

USP Digoxin RS— Dry portion in vacuum at 105

for 1 hour before using. Keep container tightly closed.

USP Dihydrocapsaicin RS— Do not dry. Keep container tightly closed. Protect from light.

USP Dihydrocodeine Bitartrate RS— Dry portion at 105

for 4 hours before using. Keep container tightly closed. Protect from light.

USP 17

-Dihydroequilin RS (C18H22O2

270.37) —Do not dry before using. Store in a cold place, protected from light. Store the contents of the opened ampul in a tightly closed container, under nitrogen, protected from light, in a cold place.

USP Dihydroergotamine Mesylate RS— Dry portion in vacuum at 100

to constant weight before using. Keep container tightly closed. Protect from light.

USP Dihydrostreptomycin Sulfate RS— Dry portion in vacuum at a pressure not exceeding 5 mm of mercury at 100

for 4 hours before using. Keep container tightly closed. Protect from light. Store in a cold place.

USP Dihydrotachysterol RS— Do not dry. Store in a cold place, protected from light. Allow to reach room temperature before opening ampuls, and use the material promptly.

USP Dihydroxyacetone RS— Do not dry. Keep container tightly closed. Store in a refrigerator.

USP Diloxanide Furoate RS— Dry portion at 105

to constant weight before using.

USP Diltiazem Hydrochloride RS— Dry portion at 105

for 2 hours before using. Keep container tightly closed. Protect from light.

USP Dimenhydrinate RS— Dry portion in vacuum over phosphorus pentoxide for 24 hours before using. Keep container tightly closed. Protect from light.

USP Dimethyl Sulfoxide RS— Do not dry. After opening, store in a tightly closed, light-resistant container. This material is extremely hygroscopic.

USP Dinoprostone RS.

USP Dinoprost Tromethamine RS— Do not dry before using. Keep container tightly closed.

USP Dioxybenzone RS— Dry portion at 40

and 5 mm of mercury for 2 hours before using. Store tightly closed, protected from light, in a cool place.

USP Diphenhydramine Citrate RS— Dry portion at 105

for 3 hours before using. Keep container tightly closed. Protect from light.

USP Diphenhydramine Hydrochloride RS— Dry portion at 105

for 3 hours before using. Keep container tightly closed. Protect from light.

USP Diphenoxylate Hydrochloride RS— Dry portion at 105

for 2 hours before using. Keep container tightly closed.

USP Dipivefrin Hydrochloride RS— Dry portion in a suitable vacuum drying tube over phosphorus pentoxide at 60

for 6 hours before using. Keep container tightly closed.

USP Dipyridamole RS— Dry portion at 105

for 3 hours before using. Keep container tightly closed. Protect from light.

USP Dirithromycin RS.

USP Disopyramide Phosphate RS— Dry portion at 105

for 4 hours before using. Keep container tightly closed. Protect from light.

USP 2,4-Disulfamyl-5-trifluoromethylaniline RS (C7H8F3N3O4S2

319.29) —Keep container tightly closed and protected from light. Dry portion in vacuum over silica gel for 4 hours before using.

USP Disulfiram RS— Do not dry before using. Keep container tightly closed. Protect from light.

USP Dobutamine Hydrochloride RS— Determine the water content titrimetrically at the time of use for quantitative analyses. Keep container tightly closed.

USP Docusate Calcium RS— Do not dry; determine the water content titrimetrically at the time of use. Keep container tightly closed. This material is hygroscopic.

USP Docusate Potassium RS— Do not dry; determine the water content at the time of use. Keep container tightly closed. Store in dry place. This material is hygroscopic.

USP Docusate Sodium RS— Do not dry; determine the water content titrimetrically at time of use. Keep container tightly closed. Store in a desiccator.

USP Dolasetron Mesylate RS— This is the monohydrate form of dolasetron mesylate. Do not dry. Keep container tightly closed.

USP Dolasetron Mesylate Related Compound A RS [hexahydro-8-hydroxy-2,6-methano-2H-quinolizin-3 (4H)-one, hydrochloride]— Do not dry. Keep container tightly closed.

USP Dopamine Hydrochloride RS— Dry portion at 105

for 2 hours before using. Keep container tightly closed.

USP Dorzolamide Hydrochloride RS— Do not dry. Keep container tightly closed.

USP Dorzolamide Hydrochloride Related Compound A RS [(4R,6R)-4-(ethylamino)-5,6-dihydro-6-methyl-4H-thieno[2,3-b]thiopyran-2-sulfonamide-7,7-dioxide, monohydrochloride] (C10H16N2O4S3·HCl

360.91) —Do not dry. Keep container tightly closed. Store in a cool room.

USP Doxapram Hydrochloride RS— Dry portion at 105

for 2 hours before using. Keep container tightly closed.

USP Doxepin Hydrochloride RS— Dry portion in vacuum at 60

for 3 hours before using. Keep container tightly closed.

USP Doxorubicin Hydrochloride RS— Do not dry before using. Store in a cold place. Protect from light, and allow to attain room temperature before opening.

USP Doxycycline Hyclate RS— Do not dry before using. Keep container tightly closed. Protect from light. Store in a cold place.

USP Doxylamine Succinate RS— Do not dry. Keep container tightly closed. Protect from light.

USP Droperidol RS— Dry portion in vacuum at 70

for 4 hours before using. Store under nitrogen. Keep container tightly closed. Protect from light. Store in a cool place.

USP Dyclonine Hydrochloride RS— Dry portion at 105

for 1 hour before using. Keep container tightly closed. Protect from light. Store in a cool place.

USP Dydrogesterone RS— Dry portion in vacuum at 50

for 1 hour before using. Keep container tightly closed.

USP Dyphylline RS— Dry portion at 105

for 3 hours before using. Keep container tightly closed.